PEDIATRIE PRO PRAXI / Pediatr. praxi. 2023;24(1):29-32 / www.pediatriepropraxi.cz 32 PŘEHLEDOVÉ ČLÁNKY Funkční dyspepsie v pediatrii Závěr Přirozený průběh FD je chronický a kolísavý s časovými obdobími, kdy je pacient asymptomatický, a následovnými epizodami relapsů. Patofyziologické mechanismy vzniku FD zahrnují viscerální hypersenzitivitu, poruchy motility žaludku, infekční, imunologické nebo psychosociální faktory, přesto všechny nejsou dosud známy. Příznaky FD zhoršují kvalitu života a komplexní léčba je indikována, pokud jednoduchá opatření, jako je ujištění o nepřítomnosti organické příčiny a dietní terapie, selžou. Specifická terapie není u dětí známa a je do značné míry symptomatická. Navzdory chronické povaze FD neexistují u dospělých žádné důkazy, které by naznačovaly, že je spojena se sníženým přežitím (1, 38, 39). Vzhledem k tomu, že děti mají významně méně komorbidit než dospělí, můžeme pro ně velmi pravděpodobně predikovat stejnou prognózu. LITERATURA 1. 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