Pediatr. pro Praxi, 2003; 1: 24-28

Role domácí a preventivní léčby v současné péči o dětské hemofiliky

MUDr. Vladimír Komrska CSc, MUDr. Kateřina Zdráhalová, Veronika Čepeláková
II. dětská klinika 2. lékařské fakulty UK a Fakultní nemocnice v Praze-Motole

Keywords: haemophilia A/B, home treatment, substitution therapy, haemophiliac arthropathy, preventive treatment.

Published: December 31, 2003  Show citation

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Komrska V, Zdráhalová K, Čepeláková V. Role domácí a preventivní léčby v současné péči o dětské hemofiliky. Pediatr. praxi. 2003;4(1):24-28.

Po obecném úvodu, který podává základní informace o hemofilii, rozebírá práce principy a metodiku domácí léčby, nutné podmínky pro ni a její praktickou realizaci. V ČR je v současnosti formou domácí léčby léčeno 48% všech dětských hemofiliků typu A a 20% všech dětských hemofiliků typu B. Procento takto léčených dětí stoupá s tíží hemofilie. Díky preventivní terapii je dnes možno i u těžkých hemofiliků zabránit vzniku invalidizující hemofilické artropatie. Smysl preventivní substituční terapie, její druhy, indikace a praktické provedení jsou uvedeny v druhé části práce. V ČR je v současnosti preventivním způsobem léčeno celkem 15,5% všech hemofiliků A a 20% všech hemofiliků B. Podobně jako u domácí léčby, i zde stoupá procento takto léčených pacientů s tíží hemofilie.

ROLE OF HOME AND PROPHYLACTIC TREATMENT IN CURRENT CARE OF CHILDREN SUFFERING FROM HAEMOPHILIA

After a general introduction providing basic information about haemophilia, this article analyses principles and procedures of home treatment and necessary conditions for its practical realization. About 48% of paediatric haemophiliacs type A and 20% of paediatric haemophiliacs type B are treated with home treatment in the Czech Republic nowadays. The percentage of children on home treatment increases with severity of haemophilia. At present due to preventive treatment, even in severe haemophiliacs it is possible to avoid development of disabling haemophiliac arthropathy. The purpose of preventive substitution therapy, its different forms, indication and practical application are mentioned in the second part of the article. In the Czech Republic at present, 15,5% of haemophiliacs A and 20% of haemophiliacs B are treated in the preventive way. Similar to home treatment, the percentage of patients treated with preventive treatment also rises with the severity of haemophilia.

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References

  1. Aledort LM. Introduction and overview of treatment. In: Miescher PA, Jaffe ER, Saunders WB (eds). Prophylaxis: A future therapy for hemophilia. Semin Hematol 1993; 30 (suppl 2): 1-2.
  2. Berntorp E. The treatment of haemophilia, including prophylaxis, constant infusion and DDAVP. In: Baillieres Clinical Haematology. Bailliere Tindall, London 1996: 2, Haemophilia, 259-273. Go to original source...
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