Pediatr. pro Praxi, 2005; 5: 247-248

RAPID PCR DIAGNOSTICS OF INVASIVE MENINGOCOCCAL DISEASE

MUDr. Jitka Kalmusová
Národní referenční laboratoř pro meningokokové nákazy, Státní zdravotní ústav, Praha

PCR (polymerase chain reaction) diagnostics is an ideal tool to be used by physicians at departments of infectious diseases, pediatric departments, intensive care units and critical care units of departments of anaesthesiology, resuscitation and intensive care. In National Reference Laboratory for Meningococcal Infections the PCR method has been introduced to detect Neisseria meningitidis, Haemophilus influenzae and Streptococcus pneumoniae. The method adds to the non-cultivation methods (direct microscopy, latex agglutination) used in serious infectious diseases diagnostics to date. It makes it possible to directly identify low-concentration pathogens in clinical material.

Keywords: Key words: polymerase chain reaction, PCR, rapid diagnostics.

Published: February 1, 2006  Show citation

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Kalmusová J. RAPID PCR DIAGNOSTICS OF INVASIVE MENINGOCOCCAL DISEASE. Pediatr. praxi. 2005;6(5):247-248.
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    References

    1. Kalmusová J, Bronská E, Křížová P. Diagnostika invazivního meningokokového, hemofilového a pneumokokového onemocnění PCR metodou. Klin mikrobiol inf lék 2004; 3:130-133.
    2. Kasal E, Rožnovský L, Křížová P, et al. Léčebný protokol invazivního meningokokového onemocnění (IMO). Prakt. Lék., 2005; 85, č. 4: 196-199.
    3. Rožnovský L, Gutvirth J, Beneš J, et al. Návrh Standardu efektivní klinické péče v přednemocniční neodkladné péči (PNP): Invazivní meningokoková onemocnění. Klin mikrobiol inf lék 2002; 8: 57-59.
    4. Strang JR, Pugh EJ. Meningococcal infections: reducing the case fatality rate by giving penicilin before admission to hospital. Br Med J 1992; 305: 143-147. Go to original source... Go to PubMed...

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