Delayed puberty is characterised by absence of physical changes of sexual development in 13 years in girls and 14 years in boys or when the pubertal development not progress appropriately: the interval between first signs of puberty and menarche in girls/completition genital growth in boys is more than 5 years. Pubertal delay is associated with short stature and bone age retardation in most patients. The aim of the assessement is to determine whether the delay or lack of development is a result of a physiological lag in normal pubertal maturation of the hypothalamo-pituitary-gonadal axis (in 50–60 %) or represents an underlying congenital or acquired abnormality.
Published: February 1, 2007 Show citation