Pediatr. praxi. 2009;10(3):169-174

Imunomodulatory effects of probiotics in clinical praxis

MUDr. Alena Kokešová, Ph.D
Klinika dětské chirurgie 2. LF UK a FN Motol, Praha

Probiotics are defined as live cultures of micro-organisms administered orally and acting beneficially on the host health. They influence

favourably both development and stability of the microflora, inhibit colonization by pathogens, influence the mucosal barrier by their

trophic effect on intestinal epithelium and stimulate both specific and non-specific components of the immune system. Understanding

the regulation of mucosal immune responses to commensal microflora and probiotics may by the key to the targeted manipulation with

microflora composition and succesful intervention in wide range of diseases in children and adults.

Keywords: probiotics, intestinal microflora, mucosal immune system.

Published: June 1, 2009  Show citation

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Kokešová A, D P. Imunomodulatory effects of probiotics in clinical praxis. Pediatr. praxi. 2009;10(3):169-174.
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