Pediatr. praxi. 2009;10(4):224-226

Venous thromboses in neonates

MUDr. Jozef Macko
Novorozenecké oddělení Krajské nemocnice T. Bati a. s., Zlín

Venous thromboses occur infrequently in the neonatal period. Given the characteristics of the neonatal coagulation activity, a neonate,

particularly a premature one, is rather predisposed to bleeding complications. However, in the context of minimum endogenous fibrinolytic

activity, every thrombotic complication is a potentially serious condition which requires adequate diagnostic and therapeutic approach.

Partial thromboses of the venous bed may not have a distinct clinical correlate and may manifest clinically later in the child‘s life. Arterial

thromboses are rare and are not dealt with in this paper; their occurrence is almost invariably linked to arterial cannulation.

Keywords: thrombosis, neonate, coagulation system.

Published: October 1, 2009  Show citation

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Macko J. Venous thromboses in neonates. Pediatr. praxi. 2009;10(4):224-226.
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    References

    1. Monagle P, Chan A, Massicotte P, Chalmers E, Michelson AD. Antithrombotic Therapy in Children: The seventh ACCP conference on antithrombotic and thrombolytic therapy. Chest 2004; 126: 645-687. Go to original source... Go to PubMed...
    2. Kosch A, Nowak-Göttl U, Günther G, Junker R, Sträter R, Schobess R, Kurnik K. Symptomatic ischemic stroke in fullterm neonates: role of acquired and genetic prothrombotic risk factors. Stroke 2000; 31: 2437-2441. Go to original source... Go to PubMed...
    3. Griffin JH, Fernandez JA, Gale AJ, Mosnier LO. Activated protein C. J Thromb Haemost 2007; 5(Suppl. 1): 73-80. Go to original source... Go to PubMed...
    4. Buffa MC, Lachassinne E. Infant perinatal thrombosis and antiphospholipid antibodies: a review. Lupus 2007; 16: 634-641. Go to original source... Go to PubMed...
    5. Bokenkamp A, von Karies R, Nowak-Gottl U, Gobel U, Hoyer PF. Neonatal renal venous thrombosis in Germany between 1992 and 1994, epidemiology, treatment and outcome. Eur J Pediatr 2000; 159: 44-48. Go to original source... Go to PubMed...
    6. Butler-O'Hara M, Buzzard CJ, Reubens L, McDermott MP, DiGrazio W, D'Angio CT. A randomized trial comparing longterm and short-term use of umbilical venous catheters in premature infants with birth weights of less than 1251 grams. Pediatrics 2006; 118: e25-e35. Go to original source... Go to PubMed...
    7. Ament L. Factor V Leiden: A review of the literature. Journal of Perinatal and Neonatal Nursing, 2003; 3: 190-195. Go to original source... Go to PubMed...
    8. Gunes AM, Baytan B, Gunay U. The influence of risk factors in promoting thrombosis during childhood: The role of acquired factors. Pediatric Hematology and Oncology 2006; 23: 399-410. Go to original source... Go to PubMed...
    9. Gerotziafas GT. Risk factors for venous thromboembolism in children. International Angiology, 2004: 23(3).
    10. Abrantes M, Lacerda AF, Abreu CR, Levy A, Azevedo A, Da Silva LJ. Cerebral venous sinus thrombosis in neonate due to factor V Leiden deficiency. Acta Paediatr 2002; 91: 243-245. Go to original source... Go to PubMed...
    11. Bertina RM, Koeleman BPC, Koster T, Rosendaal FR, Dirven RJ, de Ronde H, et al. Mutation in blood coagulation factor V associated with resistance to activated protein C. Nature 1994; 369: 64-67. Go to original source... Go to PubMed...
    12. Rees DC, Cox M, Clegg JB. World distribution of factor V Leiden. Lancet 1995; 346: 1133-1134. Go to original source... Go to PubMed...

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