Pediatr. praxi. 2014;15(1):25-27

Obsessive-compulsive disorder in childhood

MUDr.Pavel Theiner, Ph.D.
Psychiatrická klinika FN a MU Brno

The article summarizes current knowledge on obsessive-compulsive disorder (OCD). The core symptoms are obsessions and compulsions,

often accompanied by associated symptoms. The age of onset of OCD is typically the early adulthood, up to one fifth of patients

however are symptomatic before puberty. The disorder is more frequent in boys in childhood and has a better outcome than in adults.

It has been found a significant role of the orbitofrontal and anterior cingulate cortex and the basal ganglia in the pathophysiology of

OCD. One subtype may be associated with the group A streptococcal infections. The treatment is based on pharmacotherapy and cognitive-

behavioral therapy. The drugs used are serotonin reuptake inhibitors (SRI).

Keywords: obsessive-compulsive disorder, diagnosis of OCD, treatment of OCD

Published: February 15, 2014  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Theiner P. Obsessive-compulsive disorder in childhood. Pediatr. praxi. 2014;15(1):25-27.
Download citation

References

  1. Adams P. Obsessive Children. New York, Brummer/Mazel 1973: p. 193.
  2. Hudak R, Dougherty D, ed. Clinical Obsessive-Compulsive Disorders in Adults and Children. Cambridge University Press, New York 2011: 222 p.
  3. Foa EB, Kozak MJ, Goodman WK, et al. DSM-IV field trial: obsessive-compulsive disorder. Am J Psychiatry 1995; 152: 90-96. Go to original source... Go to PubMed...
  4. Hort V, Hrdlička M, Kocourková J, et al. Dětská a adolescentní psychiatrie. Praha: Portál, 2000: 496.
  5. Karno M, Golding JM, Sorenson SB, et al. The epidemiology of obsessive-compulsive disorder in five US communities. Arch Gen Psychiatry 1988, 45: 1094-1099. Go to original source... Go to PubMed...
  6. Goodman WK. Obsessive-compulsive disorder: diagnosis and treatment. J Clin Psychiatry 1999; 60(Suppl 18): 27-32. Go to original source...
  7. Horwath E, Weissman MM. The epidemiology and cross-national presentation of obsessive-compulsive disorder. Psychiatr Clin N Am 2000; 23: 493-507. Go to original source... Go to PubMed...
  8. Rasmussen SA, Eisen JL. Epidemiology of obsessive-compulsive disorder. J Clin Psychiatry 1990; 51(Suppl): 10-13.
  9. Attiullah N, Eisen LJ, Rasmussen SA. Clinical features of obsessive-compulsive disorder. Psych Clin N Am 2000; 23: 469-491. Go to original source... Go to PubMed...
  10. Grant JE, Mancebo MC, Pinto A. Late-onset obsessive compulsive disorder: clinical characteristics and psychiatric comorbidity. Psychiatry Res 2007; 30: 21-27. Go to original source... Go to PubMed...
  11. Geller DA, Biederman J, Jones J, et al. Obsessive-compulsive disorder in children and adolescents: a review. Harv Rev Psychiatry 1998; 5: 260-273. Go to original source... Go to PubMed...
  12. Stewart SE, Geller DA, Jenike M, et al. Long-term outcome of pediatric obsessive-compulsive disorder: a meta-analysis and qualitative review of the literature. Acta Psychiatr Scand 2004; 110: 3-14. Go to original source... Go to PubMed...
  13. Eisen JL, Goodman WK, Keller MB, et al. Patterns of remission and relapse in obsessive-compulsive disorder: a 2-year prospective study. J Clin Psychiatry 1999; 60: 346-351. Go to original source... Go to PubMed...
  14. Orloff LM, Battle MA, Baer L, et al. Long-term follow-up of 85 patients with obsessive-compulsive disorder. Am J Psychiatry 1994; 51: 441-442. Go to original source...
  15. Flament MF, Whitaker A, Rapoport JL, et al. Obsessive compulsive disorder in adolescence: an epidemiological study. J Am Acad Child Adolesc Psychiatry 1988; 27: 764-771. Go to original source... Go to PubMed...
  16. Montgomery SA. Clomipramine in obsessional neurosis: a placebo controlled trial. Pharmaceut Med 1980; 1: 189-192.
  17. Watson RJ, Rees CS. Meta-analysis of randomized, controlled treatment trials for pediatric obsessive-compulsive disorder. J Clin Psychol Psychiatry 2008; 49: 489-498. Go to original source... Go to PubMed...
  18. Fineberg NA, Gale TM. Evidence-based pharmacotherapy of obsessive-compulsive disorder. Int J Neuropsychopharmacol 2005; 8: 107-129. Go to original source... Go to PubMed...
  19. Fitzgerald KD, Stewart CM, Tawile V, et al. Risperidone augmentation of serotonin reuptake inhibitor treatment of pediatric obsessive compulsive disorder. J Clin Adolesc Psychopharmacol 1999; 9: 115-123. Go to original source... Go to PubMed...
  20. Thomsen PH. Risperidone augmentation in the treatment of severe adolescent OCD in SSRI-refractory cases: a case-series. Ann Clin Psychiatry 2004; 16: 201-207. Go to original source... Go to PubMed...
  21. Storch EA, Lehmkuhl H, Geffken GR, et al. Aripiprazole augmentation of incomplete treatment response in an adolescent male with obsessive-compulsive disorder. Depress Anxiety 2008; 25: 172-174. Go to original source... Go to PubMed...
  22. Praško J, Možný P, Šlepecký M, et al. Kognitivně behaviorální terapie psychických poruch. Praha: Triton, 2007: 1063 s.
  23. Neziroglu F, Henricksen J, Yaryura-Tobias J. Psychotherapy of obsessive-compulsive disorder and spectrum: Established facts and advances 1995-2005. Psychiatr Clin N Am 2006; 29: 585-604. Go to original source... Go to PubMed...
  24. POTS: Pediatric OCD treatment Study Team: Cognitive-behavioral therapy, sertraline, and their combination for children and adolescents with obsessive-compulsive disorder: the Pediatric OCD Treatment Study (POTS) randomized controlled trial. JAMA 2004; 292: 1969-1976. Go to original source... Go to PubMed...
  25. Stárková L. KBT: praktické užití v ordinaci pedopsychiatra. II. část: Obsedantně kompulzivní porucha. Psychiatrie pro praxi, 2003; 4(1): 17-19.
  26. Mezinárodní klasifikace nemocí, 10. revize. Duševní poruchy a porucha chování. Praha, Psychiatrické centrum 1992.




Pediatrics for Practice

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.