Pediatr. praxi. 2015;16(5):296-298

Antibiotic resistance in causative agents of community-acquired infections

doc.MUDr.Helena Žemličková, Ph.D.^1,2

¹ Národní referenční laboratoř pro antibiotika, Státní zdravotní ústav Praha

² Ústav klinické mikrobiologie LF UK v Hradci Králové a FN HK

Antibiotic resistance is a threat to public health and antibiotic overuse is a major factor contributing to the development and spread

of antibiotic resistance. The knowledge of the antibiotic resistance status is an important prerequisite for the appropriate choice of

antibiotic, particularly with respect to the fact that, in community-acquired infections, antibiotic therapy is indicated empirically in the

majority of cases. The results of long-term surveillance of resistance in the three most frequent bacterial agents of respiratory disease

have shown a long-term favourable situation in the drugs of choice (penicillin, amoxicillin) in Streptococcus pyogenes and Streptococcus

pneumoniae, but also increased resistance to alternative antibiotics from the macrolide group.

macrolides.

Keywords: Streptococcus pneumoniae, Streptococcus pyogenes, Haemophilus influenzae, antibiotic resistance, penicillin, amoxicillin,

Published: December 1, 2015  Show citation