Pediatr. praxi. 2017;18(1):22-26 | DOI: 10.36290/ped.2017.005

Unlicensed drug use in examples from paediatric practise

PharmDr. Kateřina Ládová, Ph.D.^{1, 2}, PharmDr. Josef Malý, Ph.D.^{1, 3}, Mgr. Milan Vegerbauer⁴, PharmDr. Petra Thomson¹

1Katedra sociální a klinické farmacie, Farmaceutická fakulta v Hradci Králové, Univerzita Karlova, 2Oddělení klinické farmacie, Nemocnice Na Homolce, Praha, 3Oddělení klinické farmacie, Nemocniční lékárna, Nemocnice Motol, Praha, 4Oddělení hromadně vyráběných léčivých přípravků, Nemocniční lékárna, Nemocnice Motol, Praha

The number of medicinal products for human use, which are not registered in the Czech Republic but used nevertheless, is constantly

increasing. There are various reasons behind the use of unlicensed medicines, notably due to medicine manufacturing and

distribution causes. This problem in the field of paediatrics arises also from the fact that clinical trials involving children are more

intricate. So as to minimize medication errors, it is crucial for healthcare professionals as well as the patients and their caregivers

to follow the good practice procedures linked with the handling of unlicensed and off-label medicines. The aim of this article is to

provide an overview of management of handling the unlicensed medicines which entails the import of unregistered medicines,

specific treatment programs and off-label use along with a few examples from the current paediatric practice.

Keywords: children, medication error, off-label, unlicensed drugs

Published: April 4, 2017  Show citation