Pediatr. praxi 2017; 18(6): 360-363 [Dermatol. praxi. 2017;11(4):174-176]

Local therapy of psoriasis

MUDr. Naděžda Vojáčková
Dermatovenerologická ambulance Praha

Psoriasis has traditionally been viewed as a primary skin condition that is treated with local agents. In light of new knowledgeon the aetiopathogenesis, psoriasis is considered to be a multifactorial disease with a number of comorbidities; therefore, theestablished patterns are gradually changing, with systemic therapy being chosen more frequently and earlier. Still, local therapycontinues to be predominant in mild and moderate forms and, in moderate and severe forms, it is an adjunct to phototherapyand systemic therapy. Traditional external medications, such as tar and cignolin, are being replaced by modern agents such asvitamin D derivatives, immunomodulators, combined drugs with corticosteroids, and retinoids.

Keywords: psoriasis, local therapy, antipsoriatics, topical corticosteroids, calcipotriol

Published: December 1, 2017  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Vojáčková N. Local therapy of psoriasis. Pediatr. praxi. 2017;18(6):360-363.
Download citation

References

  1. Bewley A, Page B. Maximizing patient adherence for optimal outcomes in psoriasis. J Eur Acad Dermatol Venereol 2011; 25(Suppl. 4): 9-14. Go to original source... Go to PubMed...
  2. Mrowietz U. Implementing treatments goals for successful long-term management of psoriasis. JEADV 2012; 26(Suppl. 2): 12-20. Go to original source... Go to PubMed...
  3. Benáková N, et al. Lokální léčba psoriázy I. Psoriasis vulgaris. Doporučené postupy české dermatovenerologické společnosti. Čes-slov Derm, 2012; 87(1): 24-32.
  4. Zschocke I, Mrowietz U, Karakasil E, et al. Non-adherence and measures to improve adherence in the topical treatment of psoriasis. JEADV 2014; 28(Suppl. 2): 4-9. Go to original source... Go to PubMed...
  5. Buckova H, Polaskova S. Psoriáza u dětí, Čes-slov Derm, 2013; 88(2): 59-72.
  6. Sklenar Z, et al. Magistraliter receptura v dermatologii. Galen 2009, ISBN 978-80-7262-588-8.
  7. Weinstein GD, Koo JY, Krueger GG, et al. Tazarotene cream in the treatment of psoriasis: Two multicenter, double-blind, randomized, vehicle-controlled studies of the safety and efficacy of tazarotene creams 0.05% and 0.1% applied once daily for 12 weeks. J Am Acad Dermatol 2003; 48: 760-767. Go to original source... Go to PubMed...
  8. Lebwohl M, Freeman AK, Chapman MS, et al. Tacrolimus ointments effective for facial and intertriginous psoriasis. J Am Acad Dermatol 2004; 51: 723-730. Go to original source... Go to PubMed...
  9. Horn EJ, Domm S, Katz HI, et al. Topical corticosteroids in psoriasis: strategies for improving safety. JEADV 2010; 24: 119-124. Go to original source... Go to PubMed...
  10. Scott LJ, Dunn CJ, Goa KL. Calcipotriol ointment. A rewiev of its use in the management of psoriasis. Am J Clin Dermatol 2001; 2(2): 95-120. Go to original source... Go to PubMed...
  11. Kerghof van de PC, Kragballe K, Saegert S, et al. Mixed treatment comparisonof a two-compound formulation product containing calcipotriol and betamethasone dipropionate with other topical treatment in psoriasis vulgaris. Cur Med Research and Opinion 2011; 27: 225-238. Go to original source... Go to PubMed...
  12. Kragballe K, Kerkhof van de PC. Pooled safety analysis of calcipotriol plus betamethasone dipropionate gel for treatment of psoriasis on the body and scalp. JEADV 2014; 28(Suppl. 2): 10-21. Go to original source... Go to PubMed...
  13. Koo J, et al. Superior efficacy of calcipotriene and betamethasone dipropionate aerosol foam versus ointment in patients with psoriasis vulgaris - a randomized phase II study.J Dermatol Treat 2016; 27(2): 120-173. Go to original source... Go to PubMed...
  14. Hong Ch, Papp KA, Lophaven KW. Patients with psoriasis have different preferences for topical therapy, highlighting the importance of individualized treatment approaches: Randomized Phase IIIb PSO-Insightful study. JEADV 2017. Go to original source...
  15. Gellmeti C. Therapeutic moisturizers as adjuvant therapy for psoriasis patients. Am J Clin Dermatol 2009; 10(Suppl 1): 7-12. Go to original source... Go to PubMed...




Pediatrics for Practice

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.