Pediatr. praxi. 2020;21(1):34-38 | DOI: 10.36290/ped.2020.002

Atopic dermatitis, part I - ethiopathogenesis, atopic march

doc. MUDr. Jarmila Čelakovská, Ph.D.
Klinika nemocí kožních a pohlavních FN a LF UK, Hradec Králové

Atopic dermatitis together with bronchial asthma and allergic rhinitis belong to the so-called atopic diseases. Atopic dermatitis is a chronic, itchy, inflammatory skin disease. Genetic predispositions, abnormal immune response and skin barrier defect are implicated in the etiopathogenesis of this disease. The course of the disease is influenced by environmental factors (such as food and inhalation allergens, infectious agents, mechanical and chemical stimuli), internal influences (hormonal influences, stress). Interest in this disease is steadily increasing, due to its increasing prevalence and adversely affecting the quality of life. The article summarizes current knowledge about atopic dermatitis and the atopic march. It gives an overview of the etiopathogenesis of atopic dermatitis, deals with the importance of food and inhallant allergy.

Keywords: atopic dermatitis, atopic march, severity of atopic dermatitis, food allergy, inhallant allergy, hygiene hypothesis.

Published: March 19, 2020  Show citation

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Čelakovská J. Atopic dermatitis, part I - ethiopathogenesis, atopic march. Pediatr. praxi. 2020;21(1):34-38. doi: 10.36290/ped.2020.002.
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