Pediatr. praxi. 2023;24(4):251-253 | DOI: 10.36290/ped.2023.065

Renal vascular thrombosis in newborn

MUDr. Nikoleta Števulová, MUDr. Josef Gut
Dětské oddělení, Nemocnice s poliklinikou Česká Lípa, a. s.

Renal vascular thrombosis is a rare disease with possible serious outcome. At least one of the three cardinal signs is present in majority of pacients: macro or microscopic hematuria, thrombocytopenia, palpable abdominal mass. The occurence of renal vein thrombosis is more common than renal arterial thrombosis. Standard diagnostic methods are ultrasound and Doppler ultrasound scan. Management and treatment options include supportive therapy, anticoagulation therapy and thrombolytic therapy, which is preferably used for organ or life threatening events. Recent diagnostic and therapeutic guidelines are illustrated by presentation of two cases of renal vein thrombosis in term newborns in the second part of the article.

Keywords: renal venous thrombosis, hematuria, newborn, renal atrophy, hypertension.

Accepted: August 21, 2023; Published: September 8, 2023  Show citation

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Števulová N, Gut J. Renal vascular thrombosis in newborn. Pediatr. praxi. 2023;24(4):251-253. doi: 10.36290/ped.2023.065.
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    References

    1. Resontoc LPR, Yap HK. Renal vascular thrombosis in the newborn. Pediatr Nephrol. 2016;31:907-915. doi.org/10.1007/s00467-015-3160-0. Go to original source... Go to PubMed...
    2. Kayemba-Kay´s S. Spontaneous neonatal renal vein thrombosis, a known pathology without clear management guidelines: An overview. Int J Pediatr Adolesc Med. 2020;7(1):31-35. doi: 10.1016/j.ijpam.2019.07.001. Go to original source... Go to PubMed...
    3. Bacciedoni V, Attie M, Donato H. Comité Nacional de Hematología, Oncología y Medicina Transfusional. Thrombosis in newborn infants. Arch Argent Pediatr. 2016;114(2):159-166. doi: 10.5546/aap.2016.eng.159. Epub 2016 Mar 2. PMID: 27079395. Go to original source... Go to PubMed...
    4. Mocková A, Huml P, Dort J, et al. Případ závažné venózní trombózy u novorozence. Pediatr. praxi. 2013;14(2):118-119.
    5. Winyard PJ, Bharucha T, De Bruyn R, et al. Perinatal renal venous thrombosis: presenting renal length predicts outcome. Arch Dis Child Fetal Neonatal Ed. 2006;91(4):F273-8. doi: 10.1136/adc.2005.083717. Epub 2006 Feb 7. PMID: 16464938; PMCID: PMC2672730. Go to original source... Go to PubMed...
    6. Ouellette AC, Darling EK, Sivapathasundaram B, et al. Incidence, Risk Factors, and Outcomes of Neonatal Renal Vein Thrombosis in Ontario: Population-Based Cohort Study. Kidney360. 2020;1(7):640-647. doi: 10.34067/KID.0000912019. Go to original source... Go to PubMed...
    7. Kosch A, Kuwertz-Bröking E, Heller Ch, et al. Renal venous thrombosis in neonates: prothrombotic risk factors and long-term follow-up. Blood. 2004;104(5):1356-1360. doi: https://doi.org/10.1182/blood-2004-01-0229. Go to original source... Go to PubMed...
    8. Zapletal O, Máchal J, Blatný J. Léčba trombotických příhod u novorozenců a kojenců. Cesko-Slovenska Pediatrie. 2020;75(2):82-90.
    9. Niada F, Tabin R, Kayemba-Kay´s S. Spontaneous neonatal renal vein thrombosis: Should we treat them all? A report of five cases and a literature review. Pediatr Neonatol. 2018;59(3):281-287. Go to original source...
    10. Monagle P, Cuello CA, Augustine C, et al. American Society of Hematology 2018 Guidelines for management of venous thromboembolism: treatment of pediatric venous thromboembolism. Blood Adv. 2018;2(22):3292-3316. doi: https://doi.org/10.1182/bloodadvances.2018024786. Go to original source... Go to PubMed...
    11. Monagle P, Newall F. Management of thrombosis in children and neonates:practical use of anticoagulants in children. Hematology Am Soc Hematol Educ Program. 2018;2018(1):399-404. doi: 10.1182/asheducation-2018.1.399. Go to original source... Go to PubMed...

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