Pediatr. praxi. 2024;25(2):102-104 | DOI: 10.36290/ped.2024.021

Wheat-dependent exercise-induced anaphylaxis

MUDr. Barbara Mílková
Alergomed, s. r. o., Třinec

Wheat-dependent exercise-induced anaphylaxis (WDEIA) is a rare but potentially serious food allergy in which anaphylaxis develops if food containing wheat is consumed within 4 hours before or shortly after physical activity. While its consumption is tolerated by the patient under other circumstances. In addition to physical exertion, some other cofactors can contribute to its development.

Keywords: food-dependent exercise-induced anaphylaxis (FDEIA), wheat-dependent exercise-induced anaphylaxis (WDEIA), anaphylaxis, gliadin.

Accepted: April 3, 2024; Published: April 8, 2024  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Mílková B. Wheat-dependent exercise-induced anaphylaxis. Pediatr. praxi. 2024;25(2):102-104. doi: 10.36290/ped.2024.021.
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Open full article

    References

    1. Beaudouin E, Renaudin JM, Morisset M, et al. Food-dependent exercise-induced anaphylaxis-update and current data. Eur Ann Allergy Clin Immunol. 2006;38(2):45-51. PMID: 16711535.
    2. Maulitz RM, Pratt DS, Schocket AL. Exercise induced anaphylactic reaction to shellfish. J Allergy Clin Immunol. 1979;63:433-434. doi: 10.1016/0091-6749(79)90218-5. Go to original source... Go to PubMed...
    3. Du Toit G. Food-dependent exercise-induced anaphylaxis in childhood. Pediatr Allergy Immunol. 2007;18(5):455-463. doi: 10.1111/j.1399-3038.2007.00599.x. PMID:17617816. Go to original source... Go to PubMed...
    4. Scherf KA, Brockow K, Biedermann T, et al. Wheat-dependent exercise-induced anaphylaxis. Clin Exp Allergy. 2016;46(1):10-20. doi: 10.1111/cea.12640. PMID: 26381478. Go to original source... Go to PubMed...
    5. Sicherer SH, Warren CM, Dant C, et al. Food Allergy from Infancy Through Adulthood. J Allergy Clin Immunol Pract. 2020;8(6):1854-1864. doi: 10.1016/j.jaip.2020.02.010. Go to original source... Go to PubMed...
    6. Tatham AS, Shewry PR. Allergens to wheat and related cereals. Clin Exp Allergy. 2008;38(11):1712-1726. doi: 10.1111/j.1365-2222.2008.03101.x. Epub 2008 Sep 24. PMID: 18823308. Go to original source... Go to PubMed...
    7. Aoki Y, Yagami A, Sakai T, et al. Alpha/Beta Gliadin MM1 Is a Novel Antigen for Wheat-Dependent Exercise-Induced Anaphylaxis. Int Arch Allergy Immunol. 2023;184(10):1022-1035. doi: 10.1159/000531056. Epub 2023 Jul 20. PMID: 37473737. Go to original source... Go to PubMed...
    8. Brockow K, Reidenbach K, Kugler C, Biedermann T. Wheat-dependent exercise-induced anaphylaxis caused by percutaneous sensitisation to hydrolysed wheat protein in cosmetics. Contact Dermatitis. 2022;87(3):296-297. doi: 10.1111/cod.14144. Epub 2022 May 19. PMID: 35524944. Go to original source... Go to PubMed...
    9. Ogino R, Chinuki Y, Yokooji T, et al. Identification of peroxidase-1 and beta-glucosidase as cross-reactive wheat allergens in grass pollen-related wheat allergy. Allergol Int. 2021;70(2):215-222. Go to original source... Go to PubMed...
    10. Schwartz HJ. Elevated serum tryptase in exercise-induced anaphylaxis. J Allergy Clin Immunol. 1995;95(4):917-919. doi: 10.1016/s0091-6749(95)70139-7. PMID: 7722176. Go to original source... Go to PubMed...
    11. Costa RJS, Snipe RMJ, Kitic CM, et al. Systematic review: exercise-induced gastrointestinal syndrome-implications for health and intestinal disease. Aliment Pharmacol Ther. 2017;46(3):246-265. doi: 10.1111/apt.14157. Epub 2017 Jun 7. PMID: 28589631. Go to original source... Go to PubMed...
    12. Casale TB, Bowman S, Kaliner M. Induction of human cutaneous mast cell degranulation by opiates and endogenous opioid peptides: evidence for opiate and nonopiate receptor participation. J Allergy Clin Immunol. 1984;73(6):775-781. Go to original source... Go to PubMed...
    13. Zogaj D, Ibranji A, Hoxha M. Exercise-induced Anaphylaxis: the Role of Cofactors. Mater Sociomed. 2014;26(6):401-404. doi:10.5455/msm.2014.26.401-404. Go to original source... Go to PubMed...
    14. Brockow K, Feldweg AM. Exercise-induced anaphylaxis: Clinical manifestations, epidemiology, pathogenesis, and diagnosis, In: UpToDate [online][cit.27-01-2024], dostupné z: https://www.uptodate.com/contents/exercise-induced-anaphylaxis-clinical-manifestations-epidemiology-pathogenesis-and-diagnosis?source=history.
    15. Zubrinich C, Puy R, O'Hehir R, et al. Evaluation of Diagnosis and Management of Omega-5- Gliadin Allergy: A Retrospective Survey. J Asthma Allergy. 2021;14:397-403. Published 2021 Apr 20. doi:10.2147/JAA.S304444. Go to original source... Go to PubMed...
    16. Christensen MJ, Eller E, Mortz CG, et al. Clinical and serological follow-up of patients with WDEIA. Clin Transl Allergy. 2019;9:26. Published 2019 May 16. doi:10.1186/s13601-019-0265-8. Go to original source... Go to PubMed...
    17. Du Z, Gao X, Li J, et al. Clinical features and outcomes of patients with wheat-dependent exercise-induced anaphylaxis: a retrospective study. Allergy Asthma Clin Immunol 18, 61 (2022). https://doi.org/10.1186/s13223-022-00702-1. Go to original source... Go to PubMed...

    Return to the content


    Pediatrics for Practice

    Madam, Sir,
    please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
    Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

    I declare:

    1. that I have met the above instruction
    2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited

    No
    Yes

    If your statement is not true, please be aware
    that brings the risk of danger to their health or the health of others.