Pediatr. praxi. 2025;26(1):14-16 | DOI: 10.36290/ped.2025.003

Introduction to the issue of acid-base balance

MUDr. Jiří Havránek¹, MUDr. Pavel Heinige², MUDr. Simona Kontuľová¹, MUDr. Lesia Kollárová¹, MUDr. Julia Formanová¹, MUDr. Andrea Navrátilová¹

¹ Dětské a novorozenecké oddělení, Nemocnice Slaný

² ODIM, Fakultní Thomayerova nemocnice a 3. LF UK, Praha

The authors of this article want to present acide-base balance in a broader context. Understanding the whole issue is imperative to clinical approach to these disorders. This article will be an introduction to the whole context. We will introduce the principle of maintaining a constant pH, as it defined by the so-called Copenhagen school. The variables (H⁺, pH, HCO₃^- a pCO₂) and their interrelation will be introduced between metabolic and respiratory disorders. In the equations below, we can not only precisely define the type of fault, but to express the presence of combinated faults and the possibility of their compensation. It can be determined whether the given disorder is acute or chronic.

Keywords: acid-base balance, respiratory and metabolic disorder, buffers, kidneys and lungs.

Accepted: March 6, 2025; Published: March 19, 2025  Show citation