Pediatr. praxi. 2007;8(6):348-352 [Dermatol. praxi. 2007;1(2):55-58]
Acne vulgaris - good practice and novelties in the pharmacological treatment
- Klinika chorob kožních a pohlavních LF UP a FN Olomouc
Acne is the most common disease affecting especially adolescents of all ethnic groups with different incidence. Prevalence is almost 100 % with differences of disease seriousness. Although not life-threatening and not a major player in clinical and laboratory research, acne markedly influences quality of life and constitutes a socioeconomic problem. Not less than 15–30 % of acne patients require medical treatment due to severity of their clinical condition, 2–7 % of them experience life long post-acne scars.
Choice of the treatment depends on severity of the clinical stage, i. e. number of skin leasions, extent or duration of the disease, and on the way of healing. Local therapy is suitable for mild forms of acne, severe forms are treated by systemic treatment in combination with topical preparations in all cases.
Keywords: acne vulgaris, topical treatment, systemic treatment
Published: January 20, 2008 Show citation
References
- Bystroň J. Perorální bakteriální imunomodulátory a medicína založená na důkazech. Alergie 2003; 5 (4): 284-290.
- Cibula D, Henzl MR, Živný J, a kol. Základy gynekologické endokrinologie. Grada Publishing, spol. s r. o., Praha 2002: 49-64.
- Cunliffe W, Gollnick H. Acne diagnosis and management. London, Martin Dunitz Ltd 2001: 80-131.
- Fanta M, Cibula D. Možnosti hormonálního ovlivnění acne vulgaris. Trendy v medicíně 2004; 5: 54-59.
- Fernandez-Obregon AC. Oral use of azithromycin for the treatment of acne. Int J Dermatol 2000; 39: 45-50.
Go to original source... 
Go to PubMed... - Gomez EC. Actions of isotretinoin and etretinate on the pilosebaceous unit. J Am Acad Dermatol 1982; 6: 746-750. Go to original source... Go to PubMed...
- Křepelka P. Kombinovaná hormonální kontracepce v léčbě akné. Akné report 2004; 2: 6.
- Plewig G, Kligman AM. Acne and Rosacea. 3rd Completely Revised and Enlarged Edition. Springer-Verlag Berlin-Heidelberg 2000: 683-689. Go to original source...
- Rulcová J, Vaněčková J, a kol. Léčba acne vulgaris. In: Kazuistiky pacientů léčených isotretinoinem. Maxdorf s r. o., Praha 2001: 7-27.
- Rulcová J. Akné - terapeutické možnosti. Trendy v medicíně 2001; 3: 3-7.
- Rulcová J. Celkově aplikovaná léčba. Referátový výběr z Dermatovenerologie, Acne vulgaris, Speciál 2004: 16-24.
- Rulcová J. Význam kombinované hormonální antikoncepce u hyperandrogenních stavů. Arch Dermatology-CZ 2004; 4(2): 106-107.
- Rulcová J. Terapeutické postupy v dermatovenerologii. Acne vulgaris. Čs Derm 2006; 81 (5): 4-12.
- Shaw JC. Hormonal therapy in dermatology. Dermatol Clin 2001; 19 (1): 169-178. Go to original source... Go to PubMed...
- Viktorinová M, Koukalová D, Karlová I, a kol. Porovnávací studie výsledků léčby akné vakcínami a systémovými antibiotiky. Čs Derm 2005; 80 (4): 224-228.
- Zouboulis CC, Korge BP, Mischke D, Orfanos CE. Altered proliferation, synthetic activity, and differentiation of cultured human sebocytes in the absence of vitamin A and their modulation by synthetic retinoids. J Invest Dermatol 1993; 101: 628-633. Go to original source... Go to PubMed...
- Zouboulis CC, Eady A, Philpott M, et al. What is the pathogenesis of acne? Exp. Dermatol 2005; 14: 143-152. Go to original source... Go to PubMed...