Pediatr. praxi. 2012;13(6):424-426
Streptococcus pneumoniae - the influence of pneumococcal conjugate vaccines on antibiotic resistance
- Národní referenční laboratoř pro antibiotika, Státní zdravotní ústav, Praha
The antibiotic resistance in Streptococcus pneumoniae is a global problem complicating the efficient therapy of pneumococcal diseases.
With the introduction of pneumococcal conjugate vaccine a reduction of prevalence of penicillin non-susceptible pneumococci has been
expected. Although the reduction especially in invasive disease caused by penicillin-resistant strains has been reported, reduction of
intermediately penicillin-resistant strains of vaccine serotypes has been compensated because of increased intermediate resistance
among non-vaccine serotypes. The reduction of antibiotic resistance among pneumococci is not possible without implementing of
complex strategies towards reduction of antibiotic use.
Keywords: Streptococcus pneumoniae, penicillin, antibiotic resistance, pneumococcal conjugate vaccine
Published: December 1, 2012 Show citation
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