Pediatr. praxi. 2015;16(1):24-27
Fractured child - recommendation for diagnostics and treatment
- Pediatrická klinika UK 2. LF a FN v Motole, Praha
The International Society for Clinical Densitometry has recently published new guidelines for diagnostics of osteoporosis in children.
These recommendations cope with the diagnostics of children with repeated fractures in a very precise and comprehensive
way. Calcium, vitamin D and an adequate physical activity are frequently used for the prophylaxis of osteoporosis, bisphosphonates
should be administered in the most severe cases. Other therapeutic possibilities (parathormone, denosumab) are a topic of upcoming
clinical studies.
Keywords: osteoporosis, bone density, calcium, vitamin D, children
Published: February 1, 2015 Show citation
References
- Hedström EM, Svensson O, Bergström U, Michno P. Epidemiology of fractures in children and adolescents. Acta Orthop 2010; 81(1): 148-153.
Go to original source... 
Go to PubMed... - Bishop N, Arundel P, Clark E, Dimitri P, Farr J, Jones G, Makitie O, Munns CF, Shaw N; International Society of Clinical Densitometry. Fracture prediction and the definition of osteoporosis in children and adolescents: the ISCD 2013 Pediatric Official Positions. J Clin Densitom 2014; 17(2): 275-280. Go to original source... Go to PubMed...
- Šumník Z, Souček O. Diagnostika osteoporózy u dětí. Pediatr.praxi 2011; 12(4): 232-234.
- Golden NH, Abrams SA. Committee on Nutrition. Optimizing bone health in children and adolescents. Pediatrics 2014; 134(4): e1229-1243. Go to original source... Go to PubMed...
- Winzenberg TM, Shaw K, Fryer J, Jones G. Calcium supplementation for improving bone mineral density in children. Cochrane Database Syst Rev. 2006 Apr 19; (2): CD005119. Go to original source... Go to PubMed...
- Shaw NJ, Mughal MZ. Vitamin D and child health: part 2 (extraskeletal and other aspects). Arch Dis Child 2013; 98(5): 368-372. Go to original source... Go to PubMed...
- Ross AC, Manson JE, Abrams SA, Aloia JF, Brannon PM, Clinton SK, Durazo-Arvizu RA, Gallagher JC, Gallo RL, Jones G, Kovacs CS, Mayne ST, Rosen CJ, Shapses SA. The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know. J Clin Endocrinol Metab 2011; 96(1): 53-58. Go to original source... Go to PubMed...
- Heaney RP, Holick MF. Why the IOM recommendations for vitamin D are deficient. J Bone Miner Res 2011; 26(3): 455-457. Go to original source... Go to PubMed...
- Winzenberg TM, Powell S, Shaw KA, Jones G. Vitamin D supplementation for improving bone mineral density in children. Cochrane Database Syst Rev 2010; (10): CD006944. Go to original source...
- Simpson M, Brady H, Yin X, Seifert J, Barriga K, Hoffman M, Bugawan T, Barón AE, Sokol RJ, Eisenbarth G, Erlich H, Rewers M, Norris JM. No association of vitamin D intake or 25-hydroxyvitamin D levels in childhood with risk of islet autoimmunity and type 1 diabetes: the Diabetes Autoimmunity Study in the Young (DAISY). Diabetologia 2011; 54(11): 2779-2788. Go to original source... Go to PubMed...
- Tenforde AS, Fredericson M. Influence of sports participation on bone health in the young athlete: a review of the literature. PM R 2011; 3(9): 861-867. Go to original source... Go to PubMed...
- Löfgren B, Dencker M, Nilsson JA, Karlsson MK. A 4-year exercise program in children increases bone mass without increasing fracture risk. Pediatrics 2012; 129(6): e1468-e1476. Go to original source... Go to PubMed...
- Dwan K, Phillipi CA, Steiner RD, Basel D. Bisphosphonate therapy for osteogenesis imperfecta. Cochrane Database Syst Rev 2014; 7: CD005088. Go to original source... Go to PubMed...
- Sumnik Z, Land C, Rieger-Wettengl G, Körber F, Stabrey A, Schoenau E. Effect of pamidronate treatment on vertebral deformity in children with primary osteoporosis. A pilot study using radiographic morphometry. Horm Res 2004; 61(3): 137-142. Go to original source... Go to PubMed...
- Boyce AM, Chong WH, Yao J, Gafni RI, Kelly MH, Chamberlain CE, Bassim C, Cherman N, Ellsworth M, Kasa-Vubu JZ, Farley FA, Molinolo AA, Bhattacharyya N, Collins MT. Denosumab treatment for fibrous dysplasia. J Bone Miner Res 2012; 27(7): 1462-1470. Go to original source... Go to PubMed...
- Semler O, Netzer C, Hoyer-Kuhn H, Becker J, Eysel P, Schoenau E. First use of the RANKL antibody denosumab in osteogenesis imperfecta type VI. J Musculoskelet Neuronal Interact 2012; 12(3): 183-188.