Pediatr. praxi. 2016;17(5):291-295 | DOI: 10.36290/ped.2016.066

The skin microbiome, new knowledge, atopic dermatitis

MUDr.Hana Zelenková, Ph.D., MBA

DOST Svidník

The Human Genome Project was aimed at reading the sequences of the entire human nuclear DNA. Currently, the sequence of more than one thousand human genomes is known, with qualified estimates giving the number at 20,488 genes. The database includes the genes of an “average individual” of a given species because the analysis always uses samples from numerous people. Every human body cell carries our genetic heritage and creates what is called the first genome. The microbiome (microflora) is an ecological community of commensal, symbiotic, and pathogenic microorganisms that share our body space. The microbiome is of vital importance for the human body, significantly affecting the health of every individual. It has evolved during mammalian evolution for millions of years and it has been shown that man lives with it in symbiosis. In this respect, the microbiome represents our second genome. The issue of microbiome is essential to the understanding of many pathological processes. In relation to dermatology, wherein the human skin is a reflection of health or illness, all research paths with a practical impact on the patient’s health are thus welcome.

Keywords: skin microbiome, emollients, atopic dermatitis

Published: November 1, 2016  Show citation