Pediatr. praxi. 2020;21(5):350-353 | DOI: 10.36290/ped.2020.071

Human milk oligosaccharides and gut microbiota

MUDr. Jan Boženský
Dětské oddělení Nemocnice AGEL Ostrava‑Vítkovice, a. s.

Human milk contains approximately 200 complex oligosaccharides believed to stimulate the growth and establishment of a protective microbiota in the infant gut. Since the discovery of human milk oligosaccharides (HMO) more than 60 years ago, research has faced a lot of problems. But in the last 10 years, there has been made progress in these areas. Based upon in vitro experiments, animal studies, and a few studies in humans, many functions of HMO have been discovered. In this article, we focus on the potential of HMO to influence the microbial composition in the gastrointestinal tract, development of children immunity or epigenetic changes, wich can influence health in adulthood.

Keywords: human milk, human milk oligosaccharides, microbiota, children immunity, epigenetic changes.

Published: October 16, 2020  Show citation

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Boženský J. Human milk oligosaccharides and gut microbiota. Pediatr. praxi. 2020;21(5):350-353. doi: 10.36290/ped.2020.071.
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