Pediatr. praxi. 2020;21(5):369-373 | DOI: 10.36290/ped.2020.076

Acute disseminated encephalomyelitis

MUDr. Martin Chvojka¹, MUDr. Josef Gut¹, MUDr. Miroslav Jiránek²

¹ Dětské oddělení Nemocnice s Poliklinikou Česká Lípa

² Dětská klinika Masarykova nemocnice v Ústí nad Labem

Acute disseminated encephalomyelitis (ADEM) is an autoimmune demyelinating disease of the central nervous system that occurs most often after an infection, typically in children and adolescents. The clinical picture is dominated by encephalopathy and various neurological deficits. Since ADEM bears resemblance to other demyelinating syndromes of childhood, the diagnosis has to be made by excluding other ethiologies, such as multiple sclerosis, although the patient history, clinical findings and imaging methods makes it readily distinguishable. Treatment of choice for ADEM is high-dose cocorticosteroids, altough intravenous immunoglobulins or plasmapheresis may be used as well. In our case report, we present eight-year-old girl with ADEM. This girl had typical findings for the disease and was a good responder to high-dose corticosteroid therapy. She made total recovery without any comlications or sequelae.

Keywords: acute disseminated encephalomyelitis, ADEM, myelin oligodendrocyte glycoprotein, corticotherapy, IVIG, plasmapheresis.

Published: October 16, 2020  Show citation