Pediatr. praxi. 2021;22(3):227-231 | DOI: 10.36290/ped.2021.045

Pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-19

MUDr. Jan Forejt, MUDr. Eva Sládková, MUDr. Michal Huml, Ph.D., prof. MUDr. Josef Sýkora Ph.D.
Dětská klinika FN a LF UK Plzeň

Authors present a new syndrome - MIS-C (multisystem inflammatory syndrome in children) in the pediatric population that has emerged within the COVID-19 pandemic. Firstly the authors share their expiriences with the syndrome on two report cases. Secondly, etiology, diagnostics and therapy of MIS-C is discussed.

Keywords: MIS-C, PIMS-TS, Kawasaki-like, fever, COVID-19.

Published: October 14, 2021  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Forejt J, Sládková E, Huml M, Sýkora J. Pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-19. Pediatr. praxi. 2021;22(3):227-231. doi: 10.36290/ped.2021.045.
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Open full article

    References

    1. Dong Y, Mo X, Hu Y, et al. Epidemiology of COVID-19 among children in China. [online] Americans Academy of Pediatrics. 16-3-2020 [cit. 25-1-2021]. Dostupné z: https://pediatrics.aappublications.org/content/145/6/e20200702 Go to original source...
    2. Bahl R, Ayesha de Costa, Diaz J, et al. Multisystem inflammatory syndrome in children and adolescents temporally related to COVID-19. In: who.int [online] Ženeva: World Health Organization, 15-5-2020 [cit. 17-1-2021]. Dostupné z: https://www.who.int/news-room/commentaries/detail/multisystem-inflammatory-syndrome-in-children-and-adolescents-with-covid-19
    3. Zimmermann P, Curtis N. Coronavirus infections in children including COVID-19: an overview of the epidemiology, clinical features, diagnosis, treatment and prevention options in children. Pediatr Infect Dis J. 2020; 39(5): 355-368. Go to original source... Go to PubMed...
    4. Lu X, Zhang L, Du H, et al. SARS-CoV-2 Infection in Children. N. Engl. J. Med. 2020; 382(17): 1663-1665. Go to original source... Go to PubMed...
    5. Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with Coronavirus Disease 2019 (COVID-19). In: cdc.gov [online] Atlanta: CDC Health Alert Network, 14-5-2020 [cit. 17-1-2021]. Dostupné z: https://emergency.cdc.gov/han/2020/han00432.asp.
    6. Jehlička P, Lád V, Sedláček D. Kawasakiho syndrom. Pediatr. praxi. 2008; 9(1): 12-14.
    7. Doležel Z, Zejdová V, Jabandžiev P, et al. Kawasakiho choroba - je nalezen specifický laboratorní ukazatel? Pediatr. praxi. 2011; 12(2): 121-123.
    8. Hoste L, Van Paemel R, Haerynck F. Multisystem inflammatory syndrome in children related to COVID-19: a systematic review. [online] European Journal of Pediatrics, 10-2-2021 [cit. 21-2-2021]. Dostupné z: https://link.springer.com/article/10.1007/s00431-021-03993-5. Go to original source...
    9. Pui Y, Day-Lewis M, Henderson L, et al. Distinct clinical and immunological features of SARS-COV-2-induced multisystem inflammatory syndrome in children. J. Clin. Investig. 2020; 130(11): 5942-5950. Go to original source... Go to PubMed...
    10. Fencl F, Šibíková M, David J. Syndrom multisystémové zánětlivé odpovědi asociovaný s COVID-19 u dětí. Doporučený postup ČPS ČLS JEP. Česko-slovenská Pediatrie. 2021; 76(1): 4-9. [cit. 24-2-2021] Dostupné z: https://www.pediatrics.cz/content/uploads/2021/01/syndrom-multisystemove-zanetlive-odpovedi-asociovany-s-covid-19-u-deti_12_1_2021.pdf
    11. Jiang L, Levin M, Irfan O. COVID-19 and multisystem inflammatory syndrome in children and adolescents. Lancet Infect. Dis. 2020; 20(11): 276-288. Go to original source... Go to PubMed...
    12. Toubiana J, Poirault C, Corsia A, et al. Kawasaki-like multi­system inflammatory syndrome in children during the covid-19 pandemic in Paris, France: prospective observational study. In: bmj.com [online]. British Medical Journal, 3-6-2020 [cit. 17-1-2021] Dostupné z: https://www.bmj.com/content/369/bmj.m2094. Go to original source... Go to PubMed...
    13. Ramcharan T, Nolan O, Lai CH. Y. Paediatric Inflammatory Multisystem Syndrome: Temporally Associated with SARS-CoV-2 (PIMS-TS): Cardiac Features, Management and Short-Term Outcomes at a UK Tertiary Paediatric Hospital. [online]. Pediatric Cardiology 12-6-2020 [cit. 12-2-2021]. Dostupné z: https://link.springer.com/article/10.1007/s00246-020-02391-2.
    14. Bertoncelli D, Guidarini M, Della Greca, et al. COVID19: potential cardiovascular issues in pediatric patients. Acta Biomed. 2020; 91(2): 177-183.

    Return to the content


    Pediatrics for Practice

    Madam, Sir,
    please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
    Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

    I declare:

    1. that I have met the above instruction
    2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited

    No
    Yes

    If your statement is not true, please be aware
    that brings the risk of danger to their health or the health of others.