Pediatr. praxi. 2023;24(1):49-52 | DOI: 10.36290/ped.2023.020

Coarctation of the aorta - still a risky and late identified defect?

MUDr. Mária Najdeková1, MUDr. Michaela Galková1, MUDr. Simona Vezérová1, MUDr. Alexandra Molnárová2, MUDr. Tomáš Gruszka1, 3, doc. MUDr. Jan Pavlíček, Ph.D.1, 3, 4
1 Klinika dětského lékařství, Fakultní nemocnice Ostrava
2 Oddělení dětského lékařství, Městská nemocnice Ostrava
3 Lékařská fakulta, Ostravská univerzita, Ostrava
4 Centrum biomedicínského výzkumu, Fakultní nemocnice Hradec Králové

Coarctation of the aorta is a significant congenital heart defect with a clinical manifestation at any time during childhood or even in adulthood. Warning or diagnostic signs include arterial hypertension, diminished femoral pulses, an arm-leg blood pressure gradient, a systolic murmur in the interscapular area and in case of a critical defect a clinical presentation of heart failure. Despite a relative simplicity of clinical diagnosis to prompt suspicion of this defect, a significant number of patients escape diagnosis until adolescence or adulthood. Coarctation of the aorta has a good prognosis. However if it is diagnosed in older age or in the presence of atypical morphology a standard operating procedure with resection and end-to-end anastomosis may not be successful and thus a more extensive procedure has to be performed. This could lead to future non-physiological circulation and more significant residues.

Keywords: coarctation of the aorta, hypertension, murmur, echocardiography.

Accepted: February 7, 2023; Published: February 20, 2023  Show citation

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Najdeková M, Galková M, Vezérová S, Molnárová A, Gruszka T, Pavlíček J. Coarctation of the aorta - still a risky and late identified defect? Pediatr. praxi. 2023;24(1):49-52. doi: 10.36290/ped.2023.020.
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References

  1. Law MA, Tivakaran VS. Coarctation of the Aorta. Stat Pearls Publishing. Available from: https://www.ncbi.nlm.nih.gov/books/NBK430913/
  2. Chaloupecký V, et al. Dětská kardiologie. Praha: Galén; 2006.
  3. Šípek A, Gregor V, Horáček J, et al. Prevalence vybraných vrozených vad v České republice: vývojové vady ledvin, srdce a vrozené chromozomové aberace. Epidemiologie, Mikrobiologie, Imunologie. 2013;62(3).
  4. Hoffman JIE, Kaplan S. The incidence of congenital heart disease. J Am Coll Cardiol. 2002;39(12):1890-1900. Go to original source... Go to PubMed...
  5. Torok RD, Campbell MJ, Fleming GA, et al. Coarctation of the aorta: management from infancy to adulthood. World J Cardiol. 2015;7(11):765-777. Go to original source... Go to PubMed...
  6. Klásková E, Tüdös Z, Wiedermann J, et al. Postižení kardiovaskulárního systému u Turnerova syndromu. Čes-slov Pediat. 2012;67(2):103-111.
  7. Malcic I, Kniewald H, Jelic A, et al. Coarctation of the aorta in children in the 10-year epidemiological study: diagnostic and therapeutic consideration. Lijec Vjesn. 2015;137: 9-17. Go to PubMed...
  8. McBride KL, Zender GA, Fitzgerald-Butt SM, et al. Linkage analysis of left ventricular outflow tract malformations (aortic valve stenosis, coarctation of the aorta, and hypoplastic left heart syndrome). Eur J Hum Genet. 2009;17:811-819. Go to original source... Go to PubMed...
  9. Ward KE, Pryor RW, Matson JR, et al. Delayed detection of coarctation in infancy: implications for timing of newborn follow-up. Pediatrics. 1990;86:972-976. Go to original source... Go to PubMed...
  10. Liberman RF, Getz KD, Lin AE, et al. Delayed diagnosis of critical congenital heart defects: trends and associated factors. Pediatrics. 2014;134:e373-e381. Go to original source... Go to PubMed...
  11. Pavlicek J, Klaskova E, Kapralova S, et al. Major heart defects: the diagnostic evaluations of first-year-olds. BMC pediatrics. 2021;21(1):1-8. Go to original source... Go to PubMed...
  12. Danworapong S, Nakwan N, Napapongsuriya C, et al. Assessing the use of pulse oximetry screening for critical congenital heart disease in asymptomatic term newborns. J Clin Neonatol. 2019;8(1):28. Go to original source...
  13. Maťašová K, Bukovinská Z, Jánoš M, et al. Skrining kritickych vrodenych chyb srdca u novorodencov pulznou oxymetriou v regione severního Slovenska. Čes-slov Pediat. 2011;66(3):146-152.
  14. Pavlíček J, Klásková E, Kaprálová S, et al. Je koarktace aorty v pediatrii rizikovou diagnózou? Čes-slov Pediat. 2019;74(8):458-464.
  15. Torok RD, Campbell MJ, Fleming GA, Hill KD. Coarctation of the aorta: management from infancy to adulthood. World J Cardiol. 2015;7(11):765-777. Go to original source... Go to PubMed...
  16. Cardoso G, Abecasis M, Anjos R, et al. Aortic coarctation repair in the adult. J Card Surg. 2014;29:512-518. Go to original source... Go to PubMed...
  17. Vrozené srdeční vady u dospělých. Popelová J. Interv Akut Kardiol. 2011;10(4):152-153.
  18. Šamánek M, Urbanová Z, Reich O, et al. Doporučení pro diagnostiku a léčbu hypertenze v dětství a dospívání. Cor Vasa. 2009;51(3):227-235. Go to original source...
  19. Petropoulos AC, Moschovi, M, Xudiyeva A, et al. Late Coarctation Presenters Suffer Chronic Hypertension Resisting to Medicine Treatment. Peertechz J Pediatr Ther. 2017;3:001-008. Go to original source...
  20. Sun Z, Cheng TO, Li L, et al. Diagnostic value of transthoracic echocardiography in patients with coarctation of aorta: the Chinese experience in 53 patients studied between 2008 and 2012 in one major medical center. PloS One. 2015;10:e0127399. Go to original source... Go to PubMed...
  21. Warnes CA, Williams RG, Bashore TM, et al. ACC/AHA 2008 Guidelines for the Management of Adults with Congenital Heart Disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (writing committee to develop guidelineson the management of adults with congenital heart disease). Circulation. 2008;118:e714-e833.




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