Pediatr. praxi. 2023;24(2):116-119 | DOI: 10.36290/ped.2023.034

Hypertension not treatable with enalapril in a boy with recurrent acute myocarditis

MUDr. Simona Ulrich¹, MUDr. Eva Drahokoupilová¹, MUDr. David Sumerauer, Ph.D.¹, MUDr. Patrik Konopásek², MUDr. Lucie Slámová, Ph.D.¹, doc. MUDr. Lucie Šrámková, Ph.D.¹

¹ Klinika dětské hematologie a onkologie, 2. LF UK a FN Motol, Praha

² Pediatrická klinika, 2. LF UK a FN Motol, Praha

Secondary hypertension in the paediatric preadolescent population prevails over primary hypertension. Although in most children, the cause is renal or cardiac, it is also necessary to consider endocrine and other factors. Here we present the case report of an 11-year-old boy, who presented predominantly with signs of acute myocarditis, and the cause of hypertension was clarified only at the second attack of these problems. A tumour was found in the retroperitoneum by ultrasound, later histologically determined to be a paraganglioma. Endogenous overproduction of catecholamines based on the presence of paraganglioma represents a very rare cause of hypertension not only in children. The biological behaviour of this tumour is malignant in 10% of patients, especially if there is a hereditary predisposition. Therefore, early detection and complex treatment of the disease are essential.

Keywords: secondary hypertension, paraganglioma, genetic predisposition.

Accepted: March 31, 2023; Published: April 5, 2023  Show citation