Pediatr. praxi. 2020;21(5):346-349 | DOI: 10.36290/ped.2020.070

Mucoactive agents in treating cough

PharmDr. MVDr. Vilma Vranová, Ph.D., PharmDr. Karel Vašut, Ph.D.
Ústav aplikované farmacie, Farmaceutická fakulta, Masarykova univerzita, Brno

Cough is a fundamental defence mechanism that maintains clear airways; moreover, phlegm production is an integral part of a non-specific protective immune response in the respiratory tract. The above facts have to be taken into account and respected when choosing an optimal cough pharmacotherapy. For mucosal healing, it is appropriate to promote mucociliary clearance, surfactant production, and other physiological functions. The action of mucoactive agents is not restricted to altering the rheological properties of mucus; these drugs also stimulate surfactant production, have antioxidant properties, reduce oxidative stress, decrease bacterial adherence, and affect the action of antibiotics.

Keywords: cough, mucoactive substances.

Published: October 16, 2020  Show citation

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Vranová V, Vašut K. Mucoactive agents in treating cough. Pediatr. praxi. 2020;21(5):346-349. doi: 10.36290/ped.2020.070.
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