Pediatr. praxi. 2021;22(4):257-260 | DOI: 10.36290/ped.2021.053

Tick-borne encephalitis and vaccination

RNDr. Helena Nejezchlebová, Ph.D., MVDr. Mgr. Monika Dušková, Ph.D., doc. RNDr. Alena Žákovská, Ph.D.
Přírodovědecká fakulta MU, Ústav experimentální biologie, Brno

Tick-borne encephalitis is an inflammatory disease of the central nervous system. The course of the disease is variable in patients, from a mild course to a severe form associated with meningitis, meningoencephalitis etc. The severity of the disease increases with age. In pediatric population, infections with a subclinical or milder course are more common compared to adults. Long-term health consequences are relatively rare. However, diagnosis is complicated by the fact that tick-borne encephalitis may mimic common diseases in children. The causative agent of the tick-borne encephalitis is a virus from the Flaviviridae family, Ixodes ricinus ticks are the main vector of this virus in the Czech Republic. Although vaccination against tick-borne encephalitis is available, vaccination coverage in the Czech Republic remains low, which is an undesirable condition associated with far-reaching medical, psychosocial and economic impacts.

Keywords: tick-borne encephalitis, sheep tick, vaccination.

Published: October 15, 2021  Show citation

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Nejezchlebová H, Dušková M, Žákovská A. Tick-borne encephalitis and vaccination. Pediatr. praxi. 2021;22(4):257-260. doi: 10.36290/ped.2021.053.
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References

  1. Evropská komise. Commission implementing decision (EU) 2018/945 of 22 June 2018 on the communicable diseases and related special health issues to be covered by epidemiological surveillance as well as relevant case definitions. Official Journal of the European Union, dostupné na https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32018D0945&from=EN#page=45 (cit. 27. 4. 2021).
  2. Lenhard T, Ott D, Jakob NJ, et al. Predictors, neuroimaging characteristics and long-term outcome of severe European tick-borne encephalitis: a prospective cohort study. PLoS One 2016; 11: e0154143. Go to original source... Go to PubMed...
  3. Velay A, Paz M, Cesbron M, et al. Tick-borne encephalitis virus: molecular determinants of neuropathogenesis of an emerging pathogen. Critical Reviews in Microbiology 2019; 45(4): 472-493. Go to original source... Go to PubMed...
  4. Evropské středisko pro prevenci a kontrolu nemocí (ECDC). Tick-borne encephalitis. Annual Epidemiological Report for 2019, dostupné na https://www.ecdc.europa.eu/sites/default/files/documents/AER-TBE-2019.pdf (cit. 27. 4. 2021).
  5. Michelitsch A, Wernike K, Klaus C, et al. Exploring the Reservoir Hosts of Tick-Borne Encephalitis Virus. Viruses 2019; 11(7): 669. Go to original source... Go to PubMed...
  6. Světová zdravotnická organizace. Vaccines against tick-borne encephalitis: WHO position paper. Weekly Epidemiological Record 2011; 86(24): 241-256. Go to PubMed...
  7. Dai X, Shang G, Lu S, et al. A new subtype of eastern tick-borne encephalitis virus discovered in Qinghai-Tibet Plateau, China. Emerging microbes & infections 2018; 7(1): 74. Go to original source... Go to PubMed...
  8. Kozlova I, Demina T, Tkachev S, et al. Characteristics of the baikal subtype of tick-borne encephalitis virus circulating in eastern Siberia. Acta Biomedica Scientifica 2018; 3: 53-60. Go to original source...
  9. Krbková L, Štroblová H, Bednářová J. Clinical course and sequelae for tick-borne encephalitis among children in South Moravia (Czech Republic). European journal of pediatrics 2015; 174(4): 449-458. Go to original source... Go to PubMed...
  10. Zambito Marsala S, Pistacchi M, Gioulis M, et al. Neurological complications of tick borne encephalitis: the experience of 89 patients studied and literature review. Neurological Sciences 2014; 35(1): 15-21. Go to original source... Go to PubMed...
  11. Steffen R. Tick-borne encephalitis (TBE) in children in Europe: Epidemiology, clinical outcome and comparison of vaccination recommendations. Ticks and Tick-borne Diseases. 2019; 10(1): 100-110. Go to original source... Go to PubMed...
  12. Steffen R. Tick-borne encephalitis - Need to eliminate misconceptions. International Journal of Infectious Diseases 2020; 101: 527-528. Go to original source...
  13. Kříž B, Beneš C, Daniel M. Alimentary transmission of tickborne encephalitis in the Czech Republic (1997-2008). Epidemiologie, Mikrobiologie, Imunologie 2009; 58(2): 98-103.
  14. Danielová V, Holubová J, Pejčoch M, Daniel M. Potential significance of transovarial transmission in the circulation of tick-borne encephalitis virus. Folia Parasitologica 2002; 49: 323-5. Go to original source... Go to PubMed...
  15. Český hydrometeorologický ústav. Předpověď aktivity klíštěte obecného pro území České republiky, dostupné na https://www.chmi.cz/predpovedi/predpovedi-pocasi/ceska-republika/predpoved-aktivity-klistat (cit. 28. 4. 2021).
  16. Földvári G, Široký P, Szekeres S, et al. Dermacentor reticulatus: a vector on the rise. Parasites 2016; 9(1): 314. Go to original source... Go to PubMed...
  17. Nejezchlebová H, Bečárová K, Žákovská A. Klíšťata a rizika přenosu nákaz z matky na plod a dítě. Pediatr. praxi 2015; 16(3): 154-155.
  18. Hönig V, Švec P, Marek L, et al. Model of Risk of Exposure to Lyme Borreliosis and Tick-Borne Encephalitis Virus-Infected Ticks in the Border Area of the Czech Republic (South Bohemia) and Germany (Lower Bavaria and Upper Palatinate). International journal of environmental research and public health 2019; 16(7). Go to original source... Go to PubMed...
  19. Amicizia D, Domnich A, Panatto D, et al. Epidemiology of tick-borne encephalitis (TBE) in Europe and its prevention by available vaccines. Human vaccines & immunotherapeutics 2013; 9(5): 1163-1171. Go to original source... Go to PubMed...
  20. Státní zdravotní ústav. Výskyt vybraných hlášených infekcí v České republice, leden - prosinec 2020, porovnání se stejným obdobím v letech 2011-2019 (počet případů), dostupné na http://www.szu.cz/uploads/documents/szu/infekce/2020/tabulka_leden_prosinec_2020.pdf (cit. 28. 4. 2021).
  21. Bröker M. Following a Tick Bite: Double Infections by Tick-Borne Encephalitis Virus and the Spirochete Borrelia and Other Potential Multiple Infections. Zoonoses and Public Health 2012; 59: 176-180. Go to original source... Go to PubMed...
  22. Logina I, Krumina A, Karelis G, et al. Clinical features of double infection with tick-borne encephalitis and lyme borreliosis transmitted by tick bite. Journal of Neurology, Neurosurgery and Psychiatry 2006; 77: 1350-1353. Go to original source... Go to PubMed...
  23. Krbková L, Homola L, Hlaváčová A, et al. Assessment of antibodies against surface and outer membrane proteins of Anaplasma phagocytophilum in Lyme borreliosis and tick-borne encephalitis paediatric patients. Epidemiology and infection 2016; 144(12): 2597-604. Go to original source... Go to PubMed...
  24. Česká vakcinologická společnost ČLS JEP. Doporučený postup České vakcinologické společnosti pro prevenci a očkování proti klíšťové encefalitidě, dostupné na https://www.vakcinace.eu/data/files/doporuceniprokevakcinaci_2016final_schvaleno_vyborem.pdf (cit. 28. 4. 2021).
  25. Heinz FX, Stiasny K, Holzmann H, et al. Vaccination and Tick-borne Encephalitis, Central Europe. Emerging Infectious Diseases. 2013; 19(1): 69-76. Go to original source... Go to PubMed...
  26. Pfizer. Příbalová informace: informace pro uživatele, dostupné na https://www.pfizer.cz/sites/pfizer.cz/files/g10039436/f/201707/FSME_Immun_025ml_PIL.pdf (cit. 28. 4. 2021).
  27. GSK Vaccines. Souhrn údajů o přípravku, dostupné na https://www.gskkompendium.cz/spc-encepur-pro-deti (cit. 28. 4. 2021).
  28. Dáňová J, Kocourková A, Čelko AM. Active surveillance study of adverse events following immunisation of children in the Czech Republic. BMC public health 2017; 17(1): 167. Go to original source... Go to PubMed...
  29. Dáňová J, Šálek J, Kocourková A, Čelko AM. Factors Associated with Parental Refusal of Routine Vaccination in the Czech Republic. Central European journal of public health 2015; 23(4): 321-323. Go to original source... Go to PubMed...
  30. Marhánková Hasmanová J, Skálová J. Kritika povinného očkování v ČR - charakteristiky rodičů a diskurzivní rámce, které využívají. Naše Společnost 2016; 1: 3-13. Go to original source...
  31. Světová zdravotnická organizace. Ten threats to global health in 2019, dostupné na https://www.who.int/news-room/spotlight/ten-threats-to-global-health-in-2019 (cit. 28. 4. 2021).
  32. Grycová L. Klíšťová encefalitida. PharmaNEWS, dostupné na http://www.pharmanews.cz/clanek/klis-ova-encefalitida-2/ (cit. 3. 5. 2021)




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