Pediatr. praxi. 2025;26(2):122-125 | DOI: 10.36290/ped.2025.023

A complicated way to an unexpected diagnosis

MUDr. Markéta Ručková1, MUDr. Petra Matalová, Ph.D.2
1 Dětské lékařství, Městská nemocnice Ostrava a Klinika dětského lékařství, Fakultní nemocnice Ostrava, Lékařská fakulta, Ostravská univerzita
2 Ústav farmakologie LF UP a FN Olomouc

A 4-year-old boy with a previously unremarkable medical history was admitted for cervical lymphadenopathy and fever. From the 3rd day of hospitalization a small-papu­lous exanthema and abdominal pain for which laparoscopic revision was necessary, phlegmonous appendicitis was found, and appendectomy was performed. Antibiotic treatment was repeatedly changed for suspected toxoallergic exanthema. Despite broad-spectrum antibiotics, inflammatory markers, transaminases continued to rise, lymphadenopathy did not significantly regress, exanthema, febrile persisted, conjunctivitis, chapped lips, arthralgia appeared. Differential diagnostic consideration was given to EB virosis, parainfectious exanthema, Kawasaki syndrome was suspected. Despite of negative findings on cardiological examination the treatment with one dose of intravenous immunoglo­bulins (IVIG) and acetylsalicylic acid (ASA) was administered. After administration of IVIG followed prompt decrease in temperature, regression of exanthema, nodal syndrome, normalization of laboratory findings. We concluded as Kawasaki syndrome.

Keywords: fever, lymphadenopathy, Kawasaki syndrome, intravenous immunoglobulins.

Accepted: May 2, 2025; Published: May 6, 2025  Show citation

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Ručková M, Matalová P. A complicated way to an unexpected diagnosis. Pediatr. praxi. 2025;26(2):122-125. doi: 10.36290/ped.2025.023.
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